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Frequency of Diabetes in Hepatitis

Introduction: The presence of hepatitis and diabetes is a known factor. Insulin resistance in muscular, hepatic and adipose tissues as well as hyperinsulinemia, seem to be pathophysiologic bases for hepatogenous diabetes. World Health Organization (WHO) ranks Pakistan 7th on diabetes prevalence list.

Objective: The objective of this study was to determine the prevalence of type 2 diabetes in chronic liver disease.

Methods: The descriptive cross-sectional survey based study was carried out at public sector government hospitals of Karachi, Pakistan. Patients with positive diagnosis of hematologic parameters were included. ANOVA was conducted to observe the difference between the clinical parameters between hepatitis B and C. Data was normally distributed as evaluated by Shapiro- Wilk test (p > 0.05). The study protocol was approved by ethical review committee.

Results: The two groups of hepatitis B and C showed statistically significant difference when compared with diabetes mellitus on chi square test. This study showed diabetes associated with HCV is more as compared to HBV.

Study Limitation: Small sample size was the study limitation.

Conclusion: diabetes associated with HCV is more as compared to HBV.

Author(s): Musleh Uddin Kalar , Ali Abbas Mohsin Ali , Sidra Ali , Syed Monis Ul Hasan , Syeda Jabeen Zahra Kazmi , Khusboo-e-Fatima , Huda Zainab Hasan , Syed Zohaib Ahsan

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